Era IV: 2009: Noir and a LOT of retreads.

Rick Eddleman pleads guilty to embezzling over $1.5 million from Depipher. The losses contributed to the company being forced to lay off more than 90 employees.

Cheapass Games awakens from ‘hibernation’ and creates the Button Men app for iPhone.

Punk

Spite: The Second Book of Pandemonium by Neoplastic Press. Enter this splatterpunk war of angels and demons.

Sci Fi

Commonwealth Space by Flying Mice. This game is set in the Cold Space/FTL Now universe, and is contemporaneous with both other games, but seen from the perspective of the Commonwealth Colonisation Agency.
Shadowrun by Catalyst Game Labs. The 20^th anniversary release of the cyberpunk game.
Rogue Trader by Fantasy Flight Games. Set in the Rogue Trader segment of the Warhammer 40,000 universe.
Doctor Who: Adventures in Time and Space by Cubicle 7 Entertainment. Once again, travel in time and space with the Doctor.
Eclipse Phase by  Catalyst Game Labs / Sandstorm Productions / Posthuman Studios. Set in an post-apocalyptic world where aliens infused our technology to work against us.
Diaspora by VSCA Publishing. In this hard-ish sci-fi game, players collaborate to develop a handful of worlds and the politics that function between them.
Judge Dredd RPG by Mongoose Publishing.
Traveller Mongoose by Mongoose Publishing. How to run Traveller using the Mongoose system.
Hardwired Hinterland by Tri Tac. A generic setting sci-fi RPG rule set.

Horror

Geist: The Sin-Eaters by White Wolf. Play a spirit bound into a once-dead person.
Noctum by Mongoose Pub and Wicked World Games. The 3^rd edition of this survivor horror RPG.
Dead Reign by Palladium Books is a post-apocalyptic zombie world RPG.

Modern / Last Century

Mutant City Blues by Pelgrane Press. 2009
Fiasco by Bully Pulpit Games. A three-act LARP-meets-RPG modern crime noir game where relationships, needs and objects are created and resolved over a game session.
Slasher Flick by Spectrum Games. What it says on the can, folks!
Beat to Quarters by Omnihedron Games. A Napolionic Era historical RPG.
Swashbucklers of the 7 Skies by  Atomic Sock Monkey / Evil Hat Productions.

Historic-esque

On Her Majesty's Arcane Service by Flying Mice. This game is set in Elizabethan England, and uses the Blood Games II game rules, being essentially a prequel to Blood Games II.
Montsegur 1244 is a game about the fall of Monstsegur Castle, held by the Cathars. The plot is pre-scripted and leads to the question which of the characters burn for heresy, and does one of them escape into the night?
Fringeworthy by . This is the 4^th edition of the alternate history game.
Chronica Feudalis by Cellar Games. In this historical game set in medieval Europe, a political, war, and social order game.

Anime

Big Eyes Small Mouth (BESM) by . This is the third (?) edition of the game.
Centauri Knights (BESM) 2009
Witch Girls Adventures by Channel M Publishing. A modern fantasy game set in the Willow-Misst High School anime.

Fantasy

FantasyCraft by Mongoose Publishing / Crafty Games. Generic fantasy game system set to the SpyCraft game engine.
Sword World 2.0 published by Fujimi Shobo, using a 2d6 system.
OpenQuest by D101 Games. A fantasy game set in the Empire of Gatan.
A Song of Ice and Fire RPG by Green Ronin Publishing. Enter Westros and play within the game of thrones.
3D&T Alpha is released, bringing the 3D&T game back from the ashes by .
Warhammer Fantasy Roleplay by FFG.
Swords & Wizardry White Box by Mythmere Games. An old-school D&D flavored boxed game.
Spellcraft & swordplay by Elf Lair Games. An old-school D&D flavored boxed game.
Earthdawn 3e by Mongoose Publishing / Redbrick. The third edition of the Earthdawn RPG.
Jaws of the Six Serpents by Silver Branch Games. A dark fantasy sword and sorcery game.
Dragon Age Set 1 by Green Ronin Publishing.
HackMaster Basic by Kenzer & co.
Shard by Shard Studios. A martial art fantasy in the world of Dardunah.
Vorkosigan Saga Sourcebook and Roleplaying Game: Sourcebook of Bujold’s Vorkosigan Saga. Part of the fictional settings set of design.

Generic / Non-genre

Ultimate Toolbox by AEG. A generic setting.
Hero System 6e by Hero Games. A generic core rule book.

GURPS Monster Hunter (var): Rules for modern ‘monster hunting’ gaming.

GURPS Martial Arts: Gladiators: Part of the fictional settings set of design.
GURPS Gun Fu: Part of the fictional settings set of design.
GURPS Lacations: Metro of Madness: Part of the fictional settings set of design.
GURPS Hot Spots: Renaissance Florence: Part of the fictional settings set of design.

From the self-published side of things…

Hyperborean Mice by Frank Sronce. Sword & Sorcery of the ancient White (mice) Lords.
Secrets & Lies by Daniel Bayn. A rules-light no DM rpg that emulates films of murder, blackmail, larceny, and extortion.